Introduction Promethazine and Codeine 6.25mg/473ml is a widely known combination medication that blends the antihistamine promethazine with the opioid codeine phosphate. This dual-action formulation is primarily prescribed to alleviate symptoms of cough, cold, and upper respiratory tract irritation, often providing sedative effects that make it appealing—but also potentially risky—for off-label use. In both New Zealand […]