Table of Contents 1. Introduction: The Evolving Landscape of Neurochemical Pain Management The discourse surrounding chronic pain management has shifted dramatically over the last decade. Historically, clinical settings relied almost exclusively on standard analgesic tiers: non-steroidal anti-inflammatory drugs (NSAIDs), followed by weak opioids, and ultimately potent mu-opioid receptor agonists. However, the systemic challenges of long-term […]