As of January 30, 2026, OxyContin 80mg, the highest-strength extended-release formulation of oxycodone hydrochloride, is among the most tightly controlled opioid analgesics worldwide. Originally designed for around-the-clock management of severe chronic pain in opioid-tolerant patients—such as those with advanced cancer, severe injury recovery, or certain degenerative conditions—this 80mg tablet releases oxycodone gradually over 12 hours […]