The honest starting point Nembutal is not a painkiller. That has to be said first, because half the people who buy it expecting analgesia are disappointed. Pentobarbital has no meaningful analgesic action at hypnotic doses. It does not touch prostaglandins, it does not act on opioid receptors, it does not block sodium channels in damaged […]
Why meth is not the awkward one Methamphetamine is the cheapest per hour of intoxication of any stimulant on earth and the most destructive per gram. That combination is why it has colonised whole regions — the American Midwest, rural Australia, swathes of Southeast Asia — and why it has never quite done so in […]
MDMA is the most-bought illegal drug in Britain after cannabis and cocaine, and the market for it is a mess of underdosed pills, over-strength pills, and pills that contain something else entirely. Where you buy it matters more than it does for almost any other substance, because the difference between a good pill and a […]
Why Britain is strange about Xanax Xanax is the most famous anxiolytic on earth and one of the least prescribed in Britain. That combination is not an accident and it is not a compliment to British medicine. Alprazolam was launched in 1981 and became, within a decade, the most-prescribed benzodiazepine in the United States. It […]
What mushroom tea actually is Mushroom tea is dried psilocybin mushroom, usually ground or shredded, blended with a flavouring base and brewed in hot water. The active compounds — psilocybin and psilocin — are water-soluble, so steeping extracts them into the cup and leaves the woody, chitinous solids behind. That is the whole premise, and […]
Start with what 600mg of codeine actually is Six hundred milligrams a day is the point where codeine stops being the harmless tablet people buy for backache. The analgesic ceiling is around 400mg; above that the extra drug buys sedation rather than pain relief, and the body has long since adjusted. Six hundred is a […]
What this strain actually is African Transkei is a Psilocybe cubensis strain collected in January 2002 on cattle dung in the shade of trees along South Africa’s Wild Coast, in the former Transkei homeland of the Eastern Cape. It is one of very few cubensis strains with a documented African origin, and the only one […]